LIVER SUPPORT

Chemical De-Tox for the Liver

LIVER SUPPORT (artichoke-liver-detox):

This is an extremely effective product for detoxifying the liver, normalizing liver metabolism preventing further damage due to internal and external toxins such as alcohol, cigarettes and environmental poisons.

Double Blind Studies have proven that patients having chronic liver disease (cirrhosis of the liver) using LIVER SUPPORT had improvements of degenerative liver damage within 30 to 90 days.

2^nd Double Blind Study

 

COMPARATIVE STUDY BETWEEN A COMPLEX OF

FLAVONOIDS AND POLYPHENOLS CREATED FROM

EXTRACTS OF ARTICHOKE AND SARSAPRILLA AND A

PLACEBO IN ALCOHOL RELATED LIVER DISEASE

 

DECEMBER 12, 1998

In a previous study, completed over two years ago in this same hospital, an extract of artichoke (Cynara Floridanum) and sarsaparilla (Smilax Aristolochiaefolia) was evaluated in addressing the symptoms related to alcoholic liver disease. This study was accomplished over a fifteen-day period with exceptional results. Because of these results noted over a very short period of time, the hospital researchers were anxious to set up the same study over a longer period (30 days). Please refer to the July 3, 1996, study for descriptions of symptoms and study parameters. Results of this study are as follows:

ASCITES

A 72.38% reduction of the accumulation of serous abdominal fluid was noted in the treated group. The placebo saw a 6.35% increase in abdominal fluid.

ENCEPHALOPATHY

A 66.08% reduction of symptoms related to encephalopathy was noted in the treated group. The placebo group saw a 12.24% increase in these symptoms.

HEPATOMEGALY

The treated group experienced a 93.33% reduction in enlarged livers. In the placebo group their livers continued to enlarge by another 7.14%.

SPLENOMEGALY

An 88.40% reduction in spleen enlargement was noted with the treated group. The placebo group worsened by 11.54%.

WEAKNESS

The treated group noted a 73.64% increase in strength. There was a decrease in muscle strength by 7.41% in the placebo group.

PERIPHERAL EDEMA

Edema in the extremities of the treated patients decreased by 48.21%. There was no change in the placebo group.

HEMORRHAGES

The treated group noted a 100% decrease in capillary hemorrhaging in the skin, gums, and nasal membranes. The placebo group saw an increase of 28.57% in hemorrhaging.

ANOREXIA

Loss of appetite decreased in the treated group by 76.98%. The placebo group noted a decrease of 3.70%.

ABDOMINAL WALL VEINS

The treated group experienced a 60.62% decrease in tortuous veins in the abdomen related to ascites. The placebo group saw a 3.33% decrease.

PALMAR ERYTHEMA

The treated group noted a 26.67% decrease in red and swollen palms. In the placebo group there was no change.

TELANGIECTASIA

A 60.00% reduction in vascular lesions was noted in the treated group. A 3.33%

reduction was seen in the placebo group.

TOTAL BILIRUBIN

The treated group noted a reduction of total bilirubin by 38.95%. The placebo group increased by 5.68%.

ALKALINE PHOSPHATASE

The treated group obtained 25.91% reduction in alkaline phosphates. There was an 11.69% increase in the placebo group.

SERUM GLUTAMIC OXALCETIC TRANSAMINASE (SGOT)

The treated group noted a decrease of 23.83% in SGOT levels. The placebo group experienced a worsening of 11.71%.

PROTHROMBIN TIME

A 42.00% reduction in clotting time was noted with the treated group. An increase in clotting time was noted in the placebo group of 6.60%.

SERUM ALBUMIN

An increase of 37.27% in serum albumin was noted in the treated group. There was a decrease in the placebo group of 1.95%.

GAMMA GLUTAMYL TRANSPEPTIDASE (GGT)

The treated group noted a reduction of 23.79% in GGT. The placebo group experienced an increase of 9.92%.

DR. CHARLES COCHRAN

1^st Double Blind Study

INTERPRETATION OF RESULTS OBTAINED IN A DOUBLE-BLIND TEST

MADE IN THE GENERAL HOSPITAL MEXICO WITH THE PRODUCT

LIVER SUPPORT ON PATIENTS HAVING CHRONIC

ALCOHOLIC HEPATIC DISEASE.

In order to analyze carefully the results of this study, it is necessary to know the importance of the two clinical and laboratory parameters intervening in the calculations of Orrego and Maddrey Indexes.

We will compare the results of parameters, the placebo and the Liver Support groups on both indexes. The results are presented as percentages of recovery and are obtained from the data obtained from each group of 30 patients, we get an average of those results at the beginning and at the end of the study. Both averages will give us a final average of recovery compared to the initial values. This way we may demonstrate the effectiveness of Liver Support.

DEFINITION AND RESULTS OF PARAMETERS

ASCITES – Effusion and accumulation of serous fluid in the abdominal cavity. It was observed 28.8% of reduction of ascites. In the placebo group there was no change.

ENCEPHALOPATHY – A degenerative disease of brain. Hepatic encephalopathy – a condition usually occurring secondarily to advanced disease of the liver. It is marked by disturbances of consciousness, which may progress to deep coma (hepatic coma), psychiatric changes of varying degree, flapping tremor and fetor hepaticas. Called also portal-systemic encephalopathy. With Liver Support there was a 34.55% reduction on encephalopathy. The placebo group a 5.5% of reduction was observed.

SPLENOMEGALIA – Enlargement of the spleen. An 18.18% of reduction in the Liver Support group and a 55% reduction in the placebo group was observed.

WEAKNESS – Lacking physical strength or vigor, asthenia, atony, cardiasthenia, enervation, fatigue, and lassitude. The group of Liver Support obtained 83.45% diminishing of weakness. There was no change in the other group.

PERIPHERAL EDEMA – A condition in which the body tissues contain an excessive amount of tissue fluid. In the Liver Support group 11.10% of reduction was observed. The placebo group has 0.69% of reduction.

HEMORRHAGES – Bleeding. This was one of the most important benefits because the group of Liver Support had a reduction of 89.41% and the placebo had 31% reduction.

ANOREXIA – Loss of appetite. Seen in depression, malaise, commencement of fevers and illnesses, also in disorders of alimentary tract, especially of stomach, and as a result of alcoholic excesses, drug addiction or many medicines. Anorexia was diminished 86.07% in the Liver Support group. There was no change in the other group.

TOTAL BILIRUBIN LEVEL – The Liver Support group obtained 25.11% reduction, whereas the placebo group had a 7.2% increase.

OGT – (Oxalacetic Glutamic Transaminase). It is distributed all over the tissues, especially in the heart and liver, less amounts are found in the spleen, pancreas, kidneys, lungs and brain. Any lesion of a tissue leads to the secretion of this enzyme to the blood stream. The activity of OGT is risen under , hepatic necrosis, cirrhosis or hepatic metastasis. In those patients who received Liver Support this level diminished 22.56%in only 15 days of treatment and in the placebo group diminished 8.51%.

PROTHROMBINE TIME – A test of clotting time made by determining the time for clotting to occur after thromboplastin and calcium are added to decalcified plasma. There was 30.82% diminishing for Liver Support patients, whereas placebo group increased –1.25%.

This is very important data, because it means that Liver Support helps the healing of wounds faster.

SERUM ALBUMIN – One of a group of simple proteins widely distributed in tissues; it is found in the blood. Low levels of albumin in blood plasma are associated with a pathologic condition of the liver. With Liver Support it was obtained an average of 8.85% of increase. The placebo had 5.35% increase.

As you know, beautiful skin is more than skin deep. The skin is the body’s largest organ of elimination. It works intimately with the liver, the largest internal organ, in helping the body to rid itself of environmental or external toxins and metabolic wastes produced by the body called internal toxins. These internal toxins come from such compounds as hormones, vitamins, cholesterol, inflammatory chemicals, and fatty acids that have served their functions and now need to be eliminated.

In this highly industrialized world that we live in, it’s impossible to breathe and eat without taking in toxic chemicals or external toxins. The Environmental Protection Agency (EPA) estimates that 500,000 chemicals are in use today, and each year over 5,000 new chemicals are added. Several sources estimate that up to 25% of these chemicals, that have been approved to be used in our environment, are cancer causing or carcinogenic. And what is even scarier is that there have been relatively few studies of the detrimental effects that these chemical substances have in our bodies when combined together. Overuse of alcohol, drugs (including prescription), and tobacco, as well as an improper diet and overeating create an additional burden to the body’s detoxification organs.

Optimum health, vitality, and beautiful skin depend to a large extent on the health and vitality of the liver. It is the body’s most complex organ carrying on over 500 functions essential for life. Blood passes through the liver at a rate of about 1.4 liters per minute, and at any instant contains about 10% of the entire blood supply. When the liver is over-stressed and starts to accumulate an excess burden of toxins, the entire detoxification process is slowed down allowing many of these poisons to continue circulating throughout the body. Some of these toxins, only partially broken down by the liver, actually become even more harmful than the original substance. In its attempt to clean up the internal environment, the body starts to look for other pathways of elimination, including the lungs, resulting in offensive breath, and the skin, resulting in disease, premature aging, and abnormal pigmentation.

One of the ways these harmful waste products damage the skin is by functioning as free radicals. Free radicals are atoms that have a missing electron in the outer orbital surrounding the nucleus. In their efforts to find and replace this missing electron, these free radicals destroy normal skin cells by stealing electrons away producing abnormal cells which now no longer function properly and die prematurely. Some of these abnormal cells start to divide at an abnormal rate and become carcinogenic. Free radical formation is also responsible for causing collagen, a protein found in the dermal layer of the skin, to become hard and cross-linked with neighboring collagen fibers, preventing it from holding water and maintaining elasticity. This cross-linked collagen then collapses on itself resulting in wrinkling of the skin. Age spots and a yellowish, old looking skin are external signs that harmful wastes are accumulating in the body due, primarily, to sluggish liver function. The slightly acid pH of the skin which provides a protective barrier against microorganisms is also altered by these poisons leaving the body unprotected and susceptible to infection.

I’m sure that you’re beginning to see that creating beautiful, healthy skin requires more than treating only what you see. Healthy skin starts on the inside with proper nutrition, relaxation and managing emotional stress, adequate sleep and exercise, elimination of dietary toxins, and support of the body’s detoxification systems. To support you and your efforts in cleaning up your internal environment and provide your skin with the protection and nutrients necessary for optimal physiological function, we have created a two-fold approach. This program treats your skin internally and externally.

Our Liver Support product is provided in a capsule form containing a proprietary comprehensive formula created from extracts of artichoke and sarsaparilla. This unique blend and extraction technique provides a rich complex of flavonoids and polyphenols that serve as anti-oxidants to prevent and protect from free radical damage due to toxins and ultraviolet exposures. These same phytochemicals have been researched in many medical studies and found to support the body’s detoxification processes and protect the liver from any future damage. By helping to relieve the burden on the detoxification systems, your skin will naturally clear and resume many younger, healthier qualities.

Not only have these flavonoids been found to protect the liver and support elimination, but they are also effective in lowering blood lipid and cholesterol levels, and providing protection from various forms of skin cancer. Also naturally occurring in this formula are phyto-estrogens which are key to tissue re-building to renew skin elasticity and remove wrinkles. Vitamin C and polyunsaturated fatty acids are also found naturally occurring in this oral formula. Vitamin C is necessary for new collagen growth and medical studies have found it to also provide UV and skin cancer protection. Medical research has found these polyunsaturated fatty acids to be effective in treating acne and eczema. Studies as far back as 1942 have shown the steroids and saponins in sarsaparilla to be of benefit in treating psoriasis.

Flavosomes, which is an ingredient in our Liver Support product, is a liquid extract created from the artichoke and sarsaparilla with several other plant pigments. A topical application provides all of the flavonoids and polyphenols, as mentioned above, and other phytonutrients that provide anti-inflammatory qualities making it suitable for dermatitis, and anti-aging features through the inhibition of free radical damage preventing skin cell damage and aging. These particular flavonoids also provide ultraviolet radiation protection and because of their ability to improve the microcirculation or small blood vessel supply to the skin, healing is accelerated and more youthful looking skin is quickly apparent. The Flavosomes have clinically been found to also have anti-microbial effects and excellent results have been noted treating such conditions as herpes simplex and yeast infections without detrimental effects to the skin’s acid mantel.

FLAVOSOMES is a proprietary formula consisting of extracts of the edible portion of the artichoke, sarsaparilla root, and several other plant pigments in liquid form developed to be used as a cosmetic ingredient. The naturally occurring flavonoids and polyphenols, including cynarin, silymarin, -(+) catechin, quercetin, kaempferol, caffeic acid, chlorogenic acid, sarsaponin, stigmasterol, and glycolic acid, have an extensive history of addressing the damage to skin brought on by chronic exposure to external and internal toxins, ultraviolet radiation, hormonal imbalances, free radical damage, and what is considered normal degenerative processes due to aging.

This complex of phytonutrients provide comprehensive protection and regenerative qualities to any skin care program by adding the following features:

• Anti-oxidant. Flavosomes inhibits free radical damage brought about by exposure to environmental pollutants, drug use, ultraviolet radiation, and improper diets. Free radical formation is responsible for causing collagen, a protein found in the dermal layer of the skin, to become hard and cross-linked with neighboring collagen fibers, preventing it from holding water and maintaining elasticity. This cross-linked collagen then collapses on itself resulting in wrinkling of the skin. Flavosomes has a group of phytonutrients, including Vitamin C, that function as anti-oxidants and neutralize these harmful free radicals to help prevent damage to the skin’s dermal layer and keep the skin hydrated, soft, and supple.
• Anti-aging. Flavosomes helps to keep the skin cell membranes resilient by providing an array of poly-unsaturated fatty acids and other fatty acids that enhance healthy cell membrane function. By normalizing cell membrane permeability, elimination of environmental and internal toxins is increased thereby preventing toxic accumulation and premature cell death.
• Anti-inflammatory. Flavosomes provides a complex of plant flavonoids that promote the binding of protein links within the cell membranes thereby supporting cellular repair, decreasing the normal healing inflammatory processes and minimizing the visible signs of aging.
• UV Filter. Flavonoids are pigments produced by the plant to carry on various functions. Some of these flavonoids are used by the plant to prevent damage due to extended exposure to harmful ultraviolet radiation from the sun. These same plant pigments, found in high concentrations in Flavosomes, offer a good natural protection and help to prevent premature aging of the skin.
• Cellular Regenerative. The flavonoids found within Flavosomes have been found to increase microcirculation to the skin, as well as decrease capillary wall fragility. By normalizing blood supply, Flavosomes supports the body’s efforts in providing adequate nutrition to the cells and at the same time, help to eliminate accumulation of metabolic and environmental toxins resulting in a smooth, youthful complexion.
• Natural Exfolient. Alpha Hydroxy Acids (AHA’s) are a group of plant or fruit acids that promote the exfoliation of dead skin cells. Studies show that, because of its size, Glycolic Acid possesses the greatest penetration potential of this entire group. Other Alpha Hydroxy Acids include malic acid, found in apples, lactic acid, found in sour milk, and tartaric acid in grapes. Glycolic Acid, found naturally occurring in the Flavosomes, helps to dissolve the "cellular cement" that binds dead cells together. Consequently, the skin’s dry, outer layer is gently sloughed away, revealing a softer, revitalized glow.
• Anti-Microbial. The flavonoids found in Flavosomes have been found to have anti-viral qualities accomplished by providing a protective coating around the skin’s cell membranes, preventing viral penetration through the skin cell membrane, and supporting the skin’s efforts in fighting infection from opportunistic microorganisms.

Ä FUNCTION AS AN ANTI-OXIDANT TO PREVENT FREE RADICAL DAMAGE

AND KEEP THE SKIN HYDRATED, SOFT, AND YOUTHFUL

Ä HELP TO NORMALIZE SKIN CELL MEMBRANE FUNCTION AND

PERMEABILITY TO PREVENT PREMATURE CELL DEATH

• PROMOTE THE BINDING FOR PROTEIN LINKS WITHIN THE CELL MEMBRANES TO DECREASE INFLAMMATION AND SUPPORT THE SKIN’S HEALING PROCESS

• PROVIDE A NATURAL PROTECTION TO THE DAMAGING EFFECTS OF

EXPOSURE TO THE SUN’S ULTRAVIOLET RADIATION DECREASING FINE LINES AND WRINKLING OF THE SKIN

• INCREASE AND PROTECT THE SKIN’S BLOOD SUPPLY TO IMPROVE

ADEQUATE NUTRITION AND ELIMINATION OF ACCUMULATED TOXINS REDUCING IRRITATION BY CALMING, COMFORTING AND NURTURING DRY SKIN

• FUNCTION AS A NATURAL EXFOLIENT TO REMOVE THE SKIN’S DEAD

CELLS THAT MIGRATE TOWARD THE SURFACE TO REVEAL THE SKIN’S HEALTHY CELLS BELOW TO CREATE A SOFT, REVITALIZED GLOW

Ä HELP TO PREVENT INFECTIONS BY FUNCTIONING AS AN ANTI-

MICROBIAL AGENT BY MEANS OF PROTECTING THE CELL MEMBRANES

FROM OPPORTUNISTIC MICROOGANISMS AND HELPING TO CLEAR

COMPLEXIONS FROM ACNE AND VIRAL INFECTIONS